Hepatitis B virus-mediated sodium influx contributes to hepatic inflammation via synergism with intrahepatic danger signals

Summary: The NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome has been involved in the Household Cleaning Products pathogenesis of various chronic liver diseases.However, its role in hepatitis B virus (HBV)-associated hepatitis remains unknown.Here we demonstrate the synergistic effect of HBV with potential intrahepatic danger

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Identification and Verification of Differential Display cDNAs Using Gene-Specific Primers and Hybridization Arrays

An accurate and streamlined approach to differential display (DD) Bins band identification and verification is described.To minimize false positives, the strategy avoids the use of impure Northern blot probes obtained from PCR-amplified DD bands.To increase throughput, the cloning of DD bands is replaced by a gene-specific primer approach, and hybr

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